| Film | Gallery | Characters |
| Includes mini-profiles on various characters from the film Slither. See also: Character category. |
Bill Pardy[]
| Slither | |
| Notability: | Main character |
| Type: | Law enforcement |
| Gender: | Male |
| Actor: | Nathan Fillion |
Brenda Gutierrez[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Female |
| Actor: | Brenda James |
Charlie[]
| Slither | |
| Notability: | Minor character |
| Gender: | Male |
| Actor: | Ben Cotton |
Dwight[]
| Slither | |
| Notability: | Minor character |
| Gender: | Male |
| Actor: | Dee Jay Jackson |
Emily Strutemyer[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Female |
| Actor: | Matreya Fedor |
Fitzgibbon[]
| Slither | |
| Notability: | Minor character |
| Gender: | Male |
| Actor: | Michael Cromien |
Grant Grant[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Male |
| Actor: | Michael Rooker |
Jack MacReady[]
| Slither | |
| Notability: | Main character |
| Type: | Mayor |
| Gender: | Male |
| Actor: | Gregg Henry |
Jenna Strutemyer[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Female |
| Actor: | Amber Lee Bartlett |
Karl[]
| Slither | |
| Notability: | Minor character |
| Type: | Doctor |
| Gender: | Male |
| Actor: | Rob Zombie |
Kylie Strutemyer[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Female |
| Actor: | Tania Saulnier |
Margaret Hooper[]
| Slither | |
| Notability: | Supporting character |
| Type: | Deputy |
| Gender: | Female |
| Actor: | Jennifer Copping |
Mister Strutemyer[]
| Slither | |
| Notability: | Minor character |
| Gender: | Male |
| Actor: | William MacDonald |
Mrs. Strutemyer[]
| Slither | |
| Notability: | Minor character |
| Gender: | Female |
| Actor: | Iris Quinn |
Shelby Cunningham[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Female |
| Actor: | Jenna Fischer |
Starla Grant[]
| Slither | |
| Notability: | Main character |
| Gender: | Female |
| Actor: | Elizabeth Banks |
Tourneur[]
| Slither | |
| Notability: | Minor character |
| Gender: | Male |
| Actor: | Tom Heaton |
Trevor Carpenter[]
| Slither | |
| Notability: | Supporting character |
| Gender: | Male |
| Actor: | Haig Sutherland |
Wally Whale[]
| Slither | |
| Notability: | Supporting character |
| Type: | Deputy |
| Gender: | Male |
| Actor: | Don Thompson |